Since TMPRSS2 plays a key role as a viral protein processing protease in the pathogenesis of other coronaviruses (SARS-CoV, MERS-CoV) as well as influenza viruses (25, 54, , , –58), MM3122 and this new class of inhibitors may be effective not only against COVID-19 but for infections caused by most or all corona and influenza viruses. The gene discussed is TMPRSS2; the disease is infection.