Preptin was higher in GDM (n = 45, 446.33 vs 157.26 pg/mL) [23], as was Secreted Frizzled-Related Protein 4 (n = 359, 12.84 vs 10.17 ng/mL) [29] and Pancreatic-derived factor (PANDER) (n = 80, 448.0 vs 140.1) [90]. The gene discussed is IGF2; the disease is gestational diabetes.