Specifically, they generated three GBM models carrying the following mutations: CDKN2A−/CDKN2B−/EGFROE/EGFRvIIIOE, NF1−/PTEN−/TP53−, and EGFRvIIIOE/CDKN2A−/PTEN−. Here, CDKN2A is linked to glioblastoma.