Moreover, the number of core miRNAs in each pathway, as the second factor, was determined to be equal to 15, 15, 11, 10, 9, 7, and 5 for p53 signaling, cell cycle, non-small cell lung cancer, ERBB signaling, WNT signaling, VEGF signaling, and TGF beta signaling pathways, respectively. The gene discussed is TP53; the disease is non-small cell lung carcinoma.