In addition to TAOK3 and STK25, the STE20-type kinases MST3 and MST4 have been associated with molecular pathogenesis of NAFLD, as evidenced by (i) protein localization to the surface of intrahepatocellular lipid droplets, (ii) inhibition of the target suppressing liver lipid accumulation in mouse models and/or cultured human hepatocytes, (iii) a significant correlation between the hepatic expression levels of the kinase and the severity of NAFLD in humans [[15], [16], [17]]. This evidence concerns the gene STK26 and metabolic dysfunction-associated steatotic liver disease.