Although GSEA revealed that M1-like TAM was enriched in immune-related, angiogenesis, EMT, and JAK-STAT3 pathways, M2 macrophages constituted the dominant population in the TAM of OC and were implicated in tumor angiogenesis, invasion, metastasis, and early recurrence [12, 22, 23]. This evidence concerns the gene STAT3 and neoplasm.