CD8A and Epstein-Barr virus infection: The disturbances of innate and adaptive immune reactions, including EBV-specific CD8 T lymphocyte (CTL) responses, are important for controlling EBV infection; therefore, in EBV-naïve recipients of SOT facing primary EBV infection during the early post-transplant period, the delay in specific anti-EBV immune response caused by T cell-targeted immunosuppression impairs control of the disease [26].