Flow cytometric analysis revealed that by day 5 post infection, when Paneth cell loss is starting to become noticeable (Raetz et al., 2013), the remaining Paneth cells while retaining MitoTracker positivity, which allows identification of all mitochondria independent of their membrane potential (Figure 6A and B, Figure 6—source data 1), were significantly compromised by day 5 post infection in an IFN-γ-dependent manner, as assessed by MitoStatus staining, which detects functionally polarized mitochondria (Figure 6A,C). The gene discussed is IFNG; the disease is infection.