In addition to the impact of CCL20 on the progression of multiple cancers, it also participates in the remodeling of the TME.18,25 Several studies have shown that CCL20 contributes to the progression of cancer by recruiting CCR6+ immune cells, such as Treg cells, dendritic cells, Th17 cells, and B cells, to the TME.26–30. Here, CCR6 is linked to cancer.