The pandemic of COVID-19, caused by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), has resulted in over 3 million deaths worldwide as of early 2021.1 The family of coronaviruses, which includes SARS-CoV-2, utilizes angiotensin-converting enzyme 2 (Ace2) as a receptor for viral attachment and intracellular entry.2,3Ace2 is expressed in a wide range of tissues including the liver,4 kidney, heart,5 lungs,2 and intestine,6 making each a potential route for viral entry and infection. The gene discussed is ACE2; the disease is infection.