CDH5 and obesity due to melanocortin 4 receptor deficiency: Obesity alters the expression of cell adhesion molecules VCAM‐1, ICAM‐1, and E‐selectin, modifying the expression of structural proteins such as pulmonary endothelial junctional adherens proteins (VE‐cadherin and β‐cathenin) by augmenting inflammation and disrupting the functions of the endothelial barrier.36