The high expression of CRABP2 may be a treatment for MPNST, and CRABP2 is not related to RA; CRABP2 has obvious nuclear staining in the normal squamous epithelium of the head and neck, but low expression in squamous cell carcinoma cells, and patients with high CRABP2 expression have longer overall survival. This evidence concerns the gene CRABP2 and malignant peripheral nerve sheath tumor.