Because brain homogenates from patients with PSP can induce tau pathology in transgenic mice expressing wild‐type human tau,6 a prion‐like propagation of spreading‐competent tau species via the extracellular cerebral compartment has been assumed to constitute an important disease mechanism in PSP and other tauopathies.4, 5, 6. Here, MAPT is linked to supranuclear palsy, progressive, 1.