Applying Pearson correlation analysis to the RNA-seq dataset of 748 glioma samples obtained from the CGGA database, we identified 10 genes positively correlated with CKAP2L (BUB1, TTK, KIF14, MELK, ASPM, KIF4A, NCAPG, BUB1B, ESCO2, and SGOL1) and 10 genes negatively correlated with CKAP2L (LDHD, FBXW4, AIFM3, ETNPPL, NOXA1, KNDC1, CYP46A1, LYNX1, MATK, and MYH7B) (Figure 9). This evidence concerns the gene ESCO2 and central nervous system cancer.