Previous studies have shown that IFN-γ has a positive effect on phagocytosis and ROS production in bovine PMNs (29), while BLV infection could reduce T cell IFN-γ expression through PD-1, Tim-3, and LAG3 pathways, which in turn affects PMN phagocytosis and respiratory burst function (30–32). The gene discussed is LAG3; the disease is deltaretrovirus infections.