CD8A and Menkes disease: LPL CD3+, CD3+CD4+, and CD3+CD8+ percentages were significantly lower in the MD group at 28 days of age than in the control group (p < 0.05), while the percentage of LPLs CD4+/CD8+ in the MD group was significantly lower than that in the control group at 42 days of age (p < 0.01) (Figures 4A1–D1).