The results demonstrated that the expression levels of OIP5-AS1, DKK3, SMOC1, and TMEM184B were significantly higher in patients with CAD, while miR-204-5p, miR-211-5p, miR-92b-3p, and miR-25-3p levels were significantly lower, which were consistent with our bioinformatic analysis (Figure 6). The gene discussed is DKK3; the disease is coronary artery disorder.