In all, we identified three novel ceRNA networks, including OIP5-AS1 - miR-204-5p/miR-211-5p - SMOC1, OIP5-AS1 - miR-92b-3p – DKK3, and OIP5-AS1 - miR-25-3p - TMEM184B, which have not been studied in CAD before. Here, DKK3 is linked to coronary artery disorder.