Currently, various plant extracts, such as mulberry leaf extracts, policosanol, CM, GTE, RES, GSPE, HON, CAP, KGM, and chlorophyll, are demonstrated to regulate serum lipid profile, inflammatory response, browning of WAT, insulin resistance, lipid and glucose metabolism, and other metabolic processes, thus improving obesity and related metabolic disorders (Table 1). Here, INS is linked to obesity due to melanocortin 4 receptor deficiency.