Moreover, in type 2 diabetic rats induced by HFD and streptozotocin, KGM administration (80 mg kg−1 body weight, for 28 days) attenuated oxidative stress by regulation of nuclear factor erythroid 2-related factor 2 (Nrf2) pathway and decreased inflammatory responses through regulating nuclear factor-kappa B (NF-κB) pathway, thus ameliorating hyperglycemia (162). The gene discussed is NFE2L2; the disease is type 2 diabetes mellitus.