For example, in the case of diffuse large B-cell lymphoma (DLBCL) and anaplastic large cell lymphoma (ALCL), pediatric patients are more likely to have GCB disease (a main subtype of DLBCL) and anaplastic lymphoma kinase (+) ALCL (ALK+ ALCL), both of which have superior prognostic features of NHL (25–27). The gene discussed is ALK; the disease is non-Hodgkin lymphoma.