In the training cohort, a significantly increased odds ratio of stage S2–4 was associated with age, NAFLD, HBV DNA, ALT, AST, ALP, GGT, total bilirubin (TBil), direct bilirubin (DBil), albumin, total cholesterol (TC), triglyceride (TG), INR, activated partial thromboplastin time (APTT), white blood cells (WBC), neutrophils, platelets, hyaluronic, laminin, PIIINP, and type IV collagen. Here, ALB is linked to metabolic dysfunction-associated steatotic liver disease.