SNHG14 and cancer: Feng et al. (2021) reported that knockdown of lncRNA in T24 cells suppressed cell proliferation, migration, and invasion, while facilitating cell apoptosis, overexpression this lncRNA shows an opposite effect. The results of bioinformatic analysis and luciferase reporter assay demonstrated that SNHG14 functions as a cancer-promoting gene by targeting miR-211-3p to regulate ESM1 expression (Feng et al., 2021). In other studies, the overexpression of SNHG14 was found to accelerate the proliferative potential by sponging miR-150-5p to degrade VAMP2 expression (Li et al., 2019).