Our earlier studies using BM and T grafts from Atg7fl/fl-FoxP3cre+ mice with disabled autophagy specifically in FoxP3+ Treg demonstrated that Treg intrinsic autophagy is required for efficient Treg reconstitution and GVHD control (Le Texier et al., 2016). This evidence concerns the gene FOXP3 and graft versus host disease.