Recent studies have reported that DUXAP8 mRNA is substantially upregulated in many cancer tissues, including pancreatic, bladder, colon, lung, ovarian, and breast cancers (Jiang et al., 2018; Lin et al., 2018; Chen et al., 2020a; He et al., 2020; Meng et al., 2020; Wang et al., 2020; Yang et al., 2021), as well as thyroid, hepatocellular and renal cell carcinomas (RCCs) (Hu et al., 2020; Wang et al., 2020; Pang and Yang, 2021), and glioma, compared to corresponding non-tumor tissues. This evidence concerns the gene DUXAP8 and renal cell carcinoma.