SLC5A2 and type 2 diabetes mellitus: Well-known examples include metformin derived from galegine, the main chemical component of European goat’s rue Galega officinalis L., for use in T2DM and dyslipidemias, as well as non-alcoholic fatty liver disease (Hundal and Inzucchi, 2003), and dapagliflozin derived from phlorizin, the main chemical constituent from roots of apple tree Malus pumila Mill., which is the first approved SGLT2 inhibitor for the treatment of T2DM, being an important option in the treatment of diabetes (Dhillon, 2019).