The exosomes secreted by the docetaxel-sensitive DU145 prostate cancer cells (DU145 tax-sen) are enriched in MDR1 (ABCB1), mdr-3, endophilin-a2, and PABP4, which are potential biomarkers of docetaxel resistance (75). This evidence concerns the gene ABCB1 and Familial prostate cancer.