IL9 and neoplasm: The interplay between MCs and MDSCs can be speculated as a builder for inflammatory tumor microenvironment as MCs secrete CCL2 which can recruit MDSCs and subsequent IL-17 secretion recruits Tregs producing IL-9 which is required for maintenance of MCs contributing to the immunosuppressive microenvironment (48, 49) making MCs as an important target for a responsive immunotherapy.