ITGAX and neoplasm: Our previous finding revealed that NF-кB inhibition in human gastric cancer cells inhibited tumor-infiltrating CD11c, F4/80, CD11b, and Gr-1-positive cells in lung and liver metastatic tissues of BALB/c nude (nu/nu) mice (14), indicating a critical role of NF-кB activation in the remodeling of tumor microenvironment.