Investigating infiltration of various immune cells in the HCC micro-environment, we demonstrated that CDT1 expression was positively correlated with the abundance of immunocytes such as T helper 2 (Th2) cells, activated dendritic cells, and T follicular helper cells, but was negatively correlated with the abundance of innate immunocytes such as neutrophils, dendritic cells, cytotoxic cells, and mast cells (Figures 10A, –G). This evidence concerns the gene CDT1 and hepatocellular carcinoma.