HES1 and pancreatic neoplasm: The expressions of the Notch1/Jagged1/Hes-1 signaling pathway components (Notch1, Jagged1, and Hes1) in PANC-1 and AsPC-1 cells were examined by qRT-PCR and Western blot tests to assess the biological relevance of SNHG7 in pancreatic cancer stemness and Folfirinox resistance.