While recent studies have only focused on ACTBL2 in a promigratory context (16, 21), our findings suggest an additional enhanced proliferative effect of Actin beta-like 2 in ovarian cancer cells, simultaneously underlining the observed correlation between high ACTBL2 expression in EOC patients and comparably fast proliferating serous carcinoma of high-grade histology. This evidence concerns the gene ACTBL2 and serous adenocarcinoma.