(34) also speculated that SLC16A1-AS1 might be involved in the occurrence and metastasis of cancer through regulation of cell cycle through three different algorithms of WGCNA, GSEA and GSVA, and verified at the cellular level that SLC16A1-AS1 silencing could inhibit the expression of cyclin D1, promote cell stagnation in G0/G1 phase, and suppress the proliferation of oral squamous cell carcinoma cells. The gene discussed is CCND1; the disease is cancer.