Mathematical modelling is a useful tool in revealing the fundamental mechanism in various cancers [5,28–31], interactions with other cells [9,32–34] including immune cells [7,35,36], cellular invasion [37], chemotherapy of cancer [35,38,39], apoptosis mechanism [6,35,40,41], and specific signalling pathways [8] such as JAK-STAT [42,43], MYC-p53 [4] and microRNAs [3]. Here, TP53 is linked to cancer.