Kubiak et al found no significant effect of 4 months supplementation of vitamin D on Apo A1 and Apo B levels.20 In another study on individuals at high risk for diabetes, Forouhi et al prescribed four doses of 100,000 IU of vitamin D for 4 months, which significantly reduced Apo B100 levels but showed no significant change in Apo A1 levels.42 Kubiak et al and Forouhi et al20,42 studies supplemented mega dosages of vitamin D for 120 days. Here, APOB is linked to diabetes mellitus.