Recent investigations have revealed that SARS-CoV-2 spike protein can bind to the ACE2 receptor.12 ACE2 is a membrane-bound aminopeptidase that is highly expressed in the heart and lungs.11 Therefore, it is suggested that SARS-CoV-2 mainly invades alveolar epithelial cells and the myocardium, resulting in respiratory and cardiovascular symptoms like dyspnea, chest pain, and arrhythmia.11 Accordingly, the mechanism of acute myocardial injury in COVID-19 might be related to ACE2.11 The gene discussed is CPQ; the disease is COVID-19.