In accordance with our results, a systematic review and meta-analysis performed by Fu et al on Chinese patients with COVID-19 indicated that the incidence proportion of increased D-dimer was 29.3%.32 Since elevated D-dimer is an independent risk factor for CVD events, it can predict the short- and long-term risks of CVD mortality.36,37 Increased levels of high-sensitivity cardiac troponin I (cTnI) along with other inflammatory biomarkers like D-dimer can be a possible reason for myocardial injury in COVID-19 patients.13 The gene discussed is TNNI3; the disease is COVID-19.