SLC12A5 and cancer: Given the lack of normal controls for some cancers in TCGA database, we used the GEPIA database containing data from both TCGA and GTEx databases to further explore the SLC12A5 expression status in pan-cancers, and as revealed in Figure 1(b), SLC12A5 was highly expressed in ACC, PAAD, CESC, DLBC, KICH, LAML, LIHC, SARC, THCA, KIRC, THYM, UCEC, KIRP, OV, and USC tissues compared with nontumor tissues, while downregulation of SLC12A5 was found in GBM and LGG (all P value < 0.05) compared with their corresponding adjacent noncancerous tissues.