Firstly, our results suggested that SLC12A5 was highly expressed in UCEC, KIRC, PAAD, ACC, CESC, DLBC, KICH, LAML, LIHC, KIRP, SARC, THCA, THYM, OV, and USC tissues compared with nontumor tissues, while it only decreased in GBM and LGG compared to their corresponding normal controls, indicating that SLC12A5 might act as a tumor promoter in human cancers. Here, SLC12A5 is linked to cervical squamous cell carcinoma.