As the first identified member family SLC17 phosphate transporter family, SLC17A1 is proposed to mediate sodium and inorganic phosphate co-transport and believed to be the voltage-driven organic anions transporter which is highly involved in renal insufficiency (Busch et al., 1996; Hollis-Moffatt et al., 2012; Iharada et al., 2010). The gene discussed is SLC17A1; the disease is Renal insufficiency.