We previously established a pre-clinical model in C57BL/6 WT mice of AML (MLL-AF9) matched to the BALB/c allogeneic donor haplotype (H2kd+), to examine the effect of venetoclax treatment with RIC on donor cell engraftment and subsequent GVT effect (8). The gene discussed is KMT2A; the disease is acute myeloid leukemia.