Patients from the allergy database at Kandang Kerbau Children’s Hospital (KKH), Singapore, with positive SPT or peanut-specific ImmunoCAP FEIA < 0.35 kUA/L were selected (2003-2006). Eligible patients completed a questionnaire. Specific serum IgE to Ara h 1, Ara h 2 and Ara h 3 was detected by ELISA. Peanut-specific IgE was detected using CAP-FEIA. This evidence concerns the gene IGHE and Allergy.