30 of 1072 children (2.8%) showed IgE sensitization to peanut, confirmed by positive SPT or high peanut-specific IgE levels (> 100 kUA/L).21 children underwent DBPCFC of which 15 had positive results.5 children had convincing medical history and supportive blood and skin test results.20 of 1072 children (1.8%) were considered to have clinical peanut allergy. The gene discussed is IGHE; the disease is peanut allergic reaction.