Univariate analysis suggested that, compared with the other cancer hallmarks such as PI3K/AKT/mTOR signaling, apoptosis, EMT, G2M checkpoint, TGF-beta signaling, angiogenesis, and hypoxia, glycolysis and immune response were the most significant risk factors affecting the survival of UM patients (Figure 2A). The gene discussed is MTOR; the disease is cancer.