AGT and myocarditis: 1Tregs reduced the migration of monocytes and promoted the polarization of macrophages to M2 macrophages (21, 52, 54).2Elimination of Tregs in I/R mice increased pro-inflammatory macrophages, accelerated ventricular dilation, and accentuated apical remodeling. Increasing Tregs in I/R mice reversed the effects (52).3In Ang II-induced hypertension mice, adoptive transfer of Tregs reduced macrophages in the heart and ameliorated cardiac damage (28).4Adoptive transfer of Tregs improved heart function in CVB3-related myocarditis (56).