Since IgG3 and IgG2 levels were different between the groups and differences in IgG3:IgG2 ratios have been observed to be important for protection in other diseases such as HIV (33), here we analyzed IgG3:IgG2 ratios in individuals with and without recurrent TB, only ratios for Hspx are shown due to the significant differences between the two groups. Here, IGHG3 is linked to tuberculosis.