After adjusting for tumor purity, in both KIRP and KIRC, PTP4A3 expression was associated with M1 macrophage markers (INOS, Cor=0.297, P=1.14E-06, Cor=0.300, P=4.83E-11; COX2, Cor=0.225, P=2.63E-04, Cor=0.233, P=4.03E-07), Th17 markers (STAT3 Cor=0.225, P=2.74E-04, Cor=0.221, P=1.62E-06) and Treg markers (TGFβ Cor=0.378, P=3.75E-11, Cor=0.502, P=8.27E-31). The gene discussed is NOS2; the disease is neoplasm.