Consistent with the results from the Oncomine database, PTP4A3 expression was significantly elevated in breast invasive carcinoma (BRCA) cholangiocarcinoma (CHOL), colon adenocarcinoma (COAD), kidney renal clear cell carcinoma (KIRC), liver hepatocellular carcinoma (LIHC), lung adenocarcinoma (LUAD), prostate adenocarcinoma (PRAD) rectum adenocarcinoma (READ) and thyroid carcinoma (THCA) relative to adjacent normal tissues (P<0.001). This evidence concerns the gene PTP4A3 and rectum adenocarcinoma.