Beyond atypical Parkinsonism, biallelic pathogenic variants in PLA2G6 are also the cause of other neurodegenerative diseases, including infantile neuroaxonal dystrophy (INAD, MIM#256600) and idiopathic neurodegeneration with brain iron accumulation, type 2 (NBIA2, MIM# 610217), all sharing many pathological and clinical features. Here, PLA2G6 is linked to Parkinson disease.