The results of qPCR validation are shown in Figure 5; the relative expression of PLD2 (t = 3.712, p = 0.003), PLAAT3 (t = 2.423, p = 0.024), and PLAAT4 (t = 4.819, p < 0.001) displayed as significantly downregulated in patients with schizophrenia compared with healthy controls, and PLCB3 (t = 0.306, p = 0.762) and CHKA (t = 1.142, p = 0.266) were found to have no significant difference. The gene discussed is PLD2; the disease is schizophrenia.