Furthermore, podocyte-endothelial cell crosstalk regulated by glucocorticoid receptor (GR) plays an important role on renal homeostasis in diabetes (Srivastava et al., 2021a; Srivastava et al., 2021b), suggesting the importance of focusing not only on the podocytes themselves, but also on the interactions between podocytes and other cells in DKD development. The gene discussed is NR3C1; the disease is diabetic kidney disease.