GHRL and Fabry disease: Therefore, it was proposed that ghrelin might be a key modulator on prokinetic effects in stomach by Yeokwisan. From the perspective of diarrhea-inducing adverse effects or clinical limitations of prokinetics (Quigley, 2015; Tack et al., 2019), these pharmacological characteristics of Yeokwisan may indicate the proper applicable spectrum of FD patients.