Combined with the serological index susceptibility genes of lung cancer queried above, we found them through literature search, Studies have shown that lncRNA PVT1 (the CA125 susceptibility gene) is involved in the regulation of immune checkpoints in a variety of tumors, including ovarian cancer, thereby promoting tumor progression (Mattick and Lee, 2009; Chen et al., 2018). The gene discussed is PVT1; the disease is lung carcinoma.