AIM2 and periodontitis: NLRP3 (Nod-like receptor pyrin domain-containing protein 3) and AIM-2 (Absent in melanoma 2) inflammasomes are associated to periodontal disease, and high levels of their receptors, NRLP3 and AIM-2, are detected in gingival tissues of periodontitis patients (Aral et al., 2021).