Logistic regression identified age (OR 6.6, CI 1.16-38.22, <i>p</i> = 0.03), plasmatic vancomycin concentrations between 96 and 144 h (OR 1.18, CI 1.04-1.40, <i>p</i> = 0.04), and urinary NGAL levels between 96 and 144 h (OR 1.123, CI 1.096-1.290, <i>p</i> = 0.03) as predictors of AKI. Here, LCN2 is linked to acute kidney injury.