The ROC curve analyses suggested an accurate diagnostic accuracy of CSF-NfL to differentiate either between other synucleinopathies (i.e., DLB and MSA) from PD as indicated by an AUC value of 0.87 or between other synucleinopathies and controls as indicated by an AUC value of 0.92. This evidence concerns the gene NEFL and Parkinson disease.